The bumper rise is due to the rising demand for the drug and patients' gradual shift towards its higher dosage.
Images from Day 2 of the fourth Test between Australia and India at the MCG on Friday.
Smith needs just 315 runs to become the fourth Australian batter after Ricky Ponting (13378), Allan Border (11174), and Steve Waugh (10927) to reach the landmark of 10,000 Test runs.
Under pressure to revive their campaign after back-to-back defeats, India will have to consider adding a sixth bowler to bring more balance to their attack when they face England in a crucial Women's ODI World Cup match, in Indore, on Sunday.
'India is much stronger in white ball than the red ball. Rohit Sharma, Virat Kohli... they know that these youngsters are pushing them.'
American Brittany Brown surprised herself with the sprint double at New York's Athlos meet on Friday, as Briton Keely Hodgkinson won the 800 metres to end her injury-dented season on a high.
Smith has rarely, if ever, doubted his own talent but even he was aware that his spell at the top of the order was proving unpopular.
Ricky Ponting advised star batters Virat Kohli and Steve Smith to stop trying hard to rediscover their best and pushing themselves too hard and just focus on watching the ball and scoring runs.
Skipper Nat Sciver-Brunt led from the front with a sparkling hundred as England beat India by 153 runs in their warm-up game ahead of the ICC Women's World Cup, in Bengaluru, on Thursday.
Anirudh Chandrasekar and Vijay Prashanth advanced to the second round of the US Open after upsetting eighth-seeded local favourites Christian Harrison and Evan King.
Having scored his 33rd ton in Brisbane, Smith equalled Sunil Gavaskar's then world record of 34 hundreds on the second day of the fourth Test at the MCG on Friday.
Australian batter Steve Smith is "focussed" on taking them all head on in the game beginning in Adelaide on Friday.
Virat Kohli and Steve Smith will be "dangerous" and "hungry" for runs in the remaining two Tests
Since going missing from red-ball action in 2021, the 30-year-old endured a period during which injuries constantly plagued him, especially a recurring stress fracture in his right elbow.
Smith took a leaf out of Hussey's book and did not train on the day before the Adelaide Test, hoping to be fresh for a big score.
Ravindra Jadeja's standout performance in the first Test against the West Indies in Ahmedabad has helped him reach a career-best 25th position in the ICC men's Test batting rankings.
Steve Smith was facing throwdowns from team-mate Marnus Labuschagne in the nets when the ball struck his right thumb.
Steve Smith has said he had never encountered a wicket like the one at the SCG
Uncapped left-arm seamer Ben Lister is likely to make his debut in the 2nd Test
R Ashwin says he has figured out ways to tackle Australian batting mainstay Steve Smith in the upcoming five-match Test series
Fulham held visitors Manchester United to a 1-1 draw in the Premier League on Sunday.
Glenn Maxwell's hopes of reviving his Test career may be over after the all-rounder missed out on selection in Australia's much-changed squad for the Sri Lanka tour.
Travis Head scored his second successive hundred while veteran Steve Smith wore the opposition down with a statement century to put Australia in control
Showing an insatiable hunger to learn and succeed, Shubman Gill turned to senior players and former greats for insights, embodying the ethos of a student of the game.
Canadian forward Olivia Smith, 20, is the first female player to break the seven-figure barrier.
Perhaps, another Ranji title with Mumbai will be a fitting send off for Ajinkya Rahane.
After a cautious start, Crawley and Duckett punished the straying Indian bowlers with an array of crisp boundaries. The pair blunted the new ball and raced to 77 without loss at tea.
England go in a happier side on Day 1 despite taking just four wickets, after Pant retired hurt injured and Sudharsan back in the hut after making 61.
Keshav Maharaj took 4/22 as South Africa thrashed a woeful England side by seven wickets after dismissing the hosts for just 131 runs in the first One-Day International.
Champions Liverpool edged Newcastle United 3-2 in a thrilling finish thanks to a stoppage-time winner by teenaged Premier League debutant Rio Ngumoha.
He also admitted to learning a lot from 'one of the best players in the world', his teammate Steve Smith.
Sai Sudharsan made the opportunity count in his comeback game with a fifty while Rishabh Pant suffered another injury as India played the old-fashioned way to reach 264 for four at stumps on Day 1 of the fourth Test in Manchester on Wednesday.
England were comfortably placed at 225 for two at stumps after bowling out India for 358 on the second day of the fourth Test in Manchester on Thursday.
South Africa's two heaviest defeats have transpired when they fielded first and were accompanied by a lack of discipline as well as dropped chances.
Earlier, after being 0-2 early in their second innings, India continued to battle on to frustrate England on day five, the tourists doing everything possible to keep the series alive on 322-4 at tea.
A rampaging England thrashed South Africa by 342 runs in the third and final ODI in Southampton on Sunday to register the biggest victory in men's One-Day Internationals.
Australia's senior batter Steve Smith said the last three years have been the most challenging because of Kookaburra changing their ball in 2020.
Rajaneesh Gupta lists the amazing numbers that make Rohit Sharma one of the finest ODI batters of his time.
Jacob Bethell has represented England in 29 matches across all formats and will lead the team in the absence of the regular Test players.
"Just Rishabh being Rishabh": Pant's grit wins hearts as he returns to bat in Manchester Test